Changing The Way We Care (“CTWWC”) is a bold initiative designed to promote safe, nurturing family care for institutionalized children or children at risk of child-family separation. This includes strengthening families and reforming national systems of care for children, including family reunification and reintegration, development of alternative family-based care (in keeping with the United Nations Guidelines for the Alternative Care of Children). CTWWC is a consortium of three partners (Catholic Relief Services, Lumos and Maestral International), joined, through a Global Development Alliance (GDA), by three donors (MacArthur Foundation, USAID and GHR Foundation). CTWWC is starting up in a context of growing interest in care reform, and as a result of a growing global understanding that institutional care of children is a significant problem that will be best addressed through collaboration between national, regional and global stakeholders to develop alternative care systems supportive of family care. Grounded in the work of three demonstration countries (Kenya, Guatemala, Moldova), as well as regional and global engagement, CTWWC will seize the momentum to help advance care for children toward and over a tipping point where government and non-government care systems, civil society initiatives, and public attitudes and behaviors focus on keeping children in safe and nurturing families.